Recombinant GOSR1/GS28 Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:: AN301536L
Additional Names:: GOSR,GOLIM,GOS28/P,GOS,GOSR1,GOLIM2,GOS-28,GOS28,GOS28/P28,GS28,P28
Application:: Flow Cytometry, IHC, WB, IF
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant human GOSR1/GS28 fragment
Clone:: A235
Uniprot:: O95249
Synonyms:: 28 kDa cis-Golgi SNARE p28;28 kDa Golgi SNARE protein;cis-golgi SNARE;golgi integral membrane protein 2;Golgi SNAP receptor complex member 1;Golgi SNARE 28 kDa;GOLIM2;GOS-28;GOS28;GOS28/P28;GS28;P28
Extra Details:: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.