AN301521L
Recombinant FBXW7 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301521L
- Additional Names:
- FBX,CDC,FBXO,hCdc,FBW,SEL,FBXW7,AGO,CDC4,FBW6,FBW7,FBX30,FBXO30,FBXW6,SEL-10,SEL10,hAgo,hCdc4,Archipelago,Archipelago homolog,DKFZp686F23254,Drosophila,Drosophila),E3 ubiquitin protein ligase,F box and WD 40 domain protein 7,F box and WD 40 domain protein 7 (archipelago homolog,F box and WD repeat domain containing 7,F box protein FBW7,F box protein FBX30,F box protein SEL 10,F box protein SEL10,F-box and WD repeat domain containing 7,F-box and WD-40 domain-containing protein 7,F-box protein
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human FBXW7 fragment
- Clone:
- A220
- Uniprot:
- Q969H0
- Synonyms:
- AGO;archipelago;Archipelago homolog;CDC4;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase;F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila);F-box and WD-40 domain-containing protein 7;F-box protein FBW7;F-box protein FBX30;F-box protein SEL-10;F-box/WD repeat-containing protein 7;FBW6;FBW7;FBX30;FBXO30;FBXW6;hAgo;hCdc4;homolog of C elegans sel-10;SEL-10;SEL10
- Extra Details:
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination.
- Shipping Conditions:
- Blue Ice