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AN301511L

Recombinant eRF3/GSPT1 Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN301511L
Additional Names:
GSPT,ERF3A,GSPT1
Application:
WB
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human eRF3/GSPT1 fragment
Clone:
A210
Uniprot:
P15170
Synonyms:
551G9.2;eRF3a;ETF3A;eukaryotic peptide chain release factor GTP-binding subunit ERF3A;eukaryotic peptide chain release factor subunit 3a;eukaryotic release factor 3a;G1 to S phase transition protein 1 homolog;GST1
Extra Details:
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
Shipping Conditions:
Blue Ice