AN301509L
Recombinant DYNLL1 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301509L
- Additional Names:
- DNCL,hdlc,Dynein Light Chain LC8-Type,DYNLL,DNCLC,DLC,DYNLL1,DLC1,DLC8,DNCL1,DNCLC1,LC8,LC8a,PIN,hdlc1,8 kDa Dynein Light Chain,Dynein Light Chain 1 Cytoplasmic,Dynein Light Chain LC8-Type 1,Protein Inhibitor of Neuronal Nitric Oxide Synthase,8kDLC,cytoplasmic,Cytoplasmic dynein light polypeptide,DYL1,Dynein,Dynein light chain 1,Dynein light chain LC8 type 1,HDLC1,LC8-type 1,light chain,light chain 1,light polypeptide 1,MGC126137,MGC126138,MGC72986,Protein inhibitor of neuronal NOS
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human DYNLL1 fragment
- Clone:
- A208
- Uniprot:
- P63167
- Synonyms:
- 8 kDa dynein light chain;cytoplasmic dynein light polypeptide;DLC1;DLC8;DNCL1;DNCLC1;dynein light chain 1, cytoplasmic;Dynein light chain LC8-type 1;dynein, cytoplasmic, light polypeptide 1;hdlc1;LC8;LC8a;PIN;protein inhibitor of neuronal nitric oxide synthase
- Extra Details:
- Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.
- Shipping Conditions:
- Blue Ice