AN301478L
Recombinant CD41 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301478L
- Additional Names:
- HPA,PPP1R,ITGA2B,BDPLT16,BDPLT2,CD41,CD41B,GP2B,GPIIb,GT,GTA,HPA3,PPP1R93,GPalpha Iib,Integrin alpha-Iib,Platelet membrane glycoprotein Iib,ITGAB,&,alpha-IIb integrin-n,BDPLT16,alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex,alpha subunit,antigen CD41,antigen CD41),form 2,Integrin,Integrin alpha 2b,Integrin alpha IIb,Integrin alpha-IIb light chain,integrin A AlphaIIbB Beta3,ITA2B,platelet fibrinogen receptor,platelet glycoprotein IIb of IIb/IIIa complex,platelet specific antigen BAK
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human CD41 fragment
- Clone:
- A173
- Uniprot:
- P08514
- Synonyms:
- alphaIIb protein;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPalpha IIb;GPIIb;GT;GT1;GTA;HPA3;integrin alpha-IIb;integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41);platelet fibrinogen receptor, alpha subunit;platelet glycoprotein IIb of IIb/IIIa complex;platelet membrane glycoprotein IIb;platelet-specific antigen BAK;PPP1R93;protein phosphatase 1, regulatory subunit 93
- Extra Details:
- Integrin A Alpha-IIb/B Beta-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bond-connected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness.
- Shipping Conditions:
- Blue Ice