AN301473L
Recombinant CD278/ICOS Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301473L
- Additional Names:
- CVID,ICOS,AILIM,CD278,CVID1,activation-inducible lymphocyte immunomediatory molecule,Inducible T-cell costimulator
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human CD278/ICOS fragment
- Clone:
- A168
- Uniprot:
- Q9Y6W8
- Synonyms:
- activation-inducible lymphocyte immunomediatory molecule;AILIM;CD278;CVID1;inducible costimulator;inducible T-cell co-stimulator;inducible T-cell costimulator
- Extra Details:
- Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
- Shipping Conditions:
- Blue Ice