AN301442L
Recombinant B7-H3/CD276 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301442L
- Additional Names:
- B7H,UNQ,PRO,B7-H,B7RP,B7 homolog,B7H34Ig-B7-H,PSEC,4Ig-B7-H,CD276,4Ig-B7-H3,B7-H3,B7H3,B7RP-2,B7 homolog 3,B7H34Ig-B7-H3,CD276 antigen,CD276 molecule,Costimulatory molecule,PSEC0249,UNQ309,PRO352,B7RP-2,4Ig-B7-H3,B7H3,B7-H3,CD276 antigen
- Application:
- Flow Cytometry, IHC, WB, IF, IP
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human B7-H3/CD276 fragment
- Clone:
- A137
- Uniprot:
- Q5ZPR3
- Synonyms:
- 4Ig-B7-H3;B7 homolog 3;B7-H3;B7H3;B7RP-2;CD276 antigen;costimulatory molecule
- Extra Details:
- May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
- Shipping Conditions:
- Blue Ice