AN301433L
Recombinant alpha Actinin 4 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301433L
- Additional Names:
- ACTN,Non-muscle alpha-actinin,ACTININ,ACTN4,ACTININ-4,FSGS,FSGS1,Non-muscle alpha-actinin 4,actinin 4,Actinin alpha 4,actinin4,ACTN 4,Alpha-actinin-4,DKFZp686K23158,F actin cross linking protein,F-actin cross-linking protein,Focal segmental glomerulosclerosis 1,FSGS 1,Non muscle alpha actinin 4
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human Actinin 4 fragment
- Clone:
- A128
- Uniprot:
- O43707
- Synonyms:
- ACTININ-4;alpha-actinin-4;focal segmental glomerulosclerosis 1;FSGS;FSGS1;non-muscle alpha-actinin 4
- Extra Details:
- F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.
- Shipping Conditions:
- Blue Ice