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AN301406L

Recombinant Histone H2B (Acetyl Lys46) Monoclonal Antibody

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£252.90

Was £281.00

SKU:
AN301406L
Additional Names:
HIST1H2BG,H2B.1A,H2B/a,H2BFA,H2BFL,HIST1H2BC,H2BFH,HIST1H2BE,H2BFG,HIST1H2BF,H2BFK,HIST1H2BI,H2BC4,H2BC6,H2BC7,H2BC8,H2BC10
Application:
ChIP, WB, IF
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Acetylated human histone H2B (Lys46) peptide
Clone:
A101
Uniprot:
P62807
Synonyms:
dJ221C16.3;dJ221C16.6;dJ221C16.8;H2B histone family, member A;H2B histone family, member B;H2B histone family, member G;H2B histone family, member H;H2B histone family, member K;H2B histone family, member L;H2B.1;H2B.1A;H2B.1B;H2B.h;H2B/a;H2B/b;H2B/g;H2B/h;H2B/k;H2B/l;H2BC10;H2BC4;H2BC6;H2BC7;H2BC8;H2BFA;H2BFB;H2BFG;H2BFH;H2BFK;H2BFL;HIRA-interacting protein 2;HIRIP2;HIST1H2BC;HIST1H2BD;HIST1H2BE;HIST1H2BF;HIST1H2BG;HIST1H2BI;histone 1, H2bc;histone 1, H2bd;histone 1, H2be;histone 1, H2bf;histone 1, H2bg;histone 1, H2bi;histone cluster 1 H2B family member c;histone cluster 1 H2B family member d;histone cluster 1 H2B family member e;histone cluster 1 H2B family member f;histone cluster 1 H2B family member g;histone cluster 1 H2B family member i;histone cluster 1, H2bc;histone cluster 1, H2bd;histone cluster 1, H2be;histone cluster 1, H2bf;histone cluster 1, H2bg;histone cluster 1, H2bi;Histone H2B type 1-C/E/F/G/I;histone H2B type 1-D;Histone H2B.1 A;histone H2B.1 B;Histone H2B.a;histone H2B.b;Histone H2B.g;Histone H2B.h;Histone H2B.k;Histone H2B.l
Extra Details:
Histone post-translational modifications (PTMs) are key mechanisms of epigenetics that modulate chromatin structures, termed as "histone code". The PTMs on histone including acetylation, methylation, phosphorylation and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability, gene transcription, etc. Histone acetylation occurs primarily at multiple lysine residues on the amino-terminal of core histones, in response to various stimuli and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc. Mostly, histone H2A is primarily acetylated at Lys5, 9, 15, and 36, H2B is primarily acetylated at Lys5, 12, 15, 16, and 20. Histone H3 is primarily acetylated at Lys4, 9, 14, 18, 23, 27, 56, and 79. Histone H4 is primarily acetylated at Lys5, 8, 12, 16, and 20. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are major regulating factors.
Shipping Conditions:
Blue Ice