Recombinant Phospho-PLCG Gamma1 (Tyr783) Monoclonal Antibody

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£311.40

Was £346.00

SKU:: AN301390L
Additional Names:: PLCG,phospholipase C gamma,NCKAP,PLCgamma,PLC,PLCG1,NCKAP3,PLC-II,PLC1,PLC148,PLCgamma1,phospholipase C gamma 1,NCKAP3,phospholipase C gamma 1,PLC1,PLC148,PLCgamma1,PLC-II,PLCG1
Application:: WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: A synthetic peptide corresponding to residues around (Tyr783) of Human Phospho-PLCG Gamma1
Clone:: B1157
Uniprot:: P19174
Synonyms:: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;inositoltrisphosphohydrolase;monophosphatidylinositol phosphodiesterase;NCKAP3;phosphatidylinositol phospholipase C;phosphoinositidase C;phosphoinositide phospholipase C;phosphoinositide phospholipase C-gamma-1;phospholipase C-148;Phospholipase C-gamma-1;phospholipase C-II;phospholipase C, gamma 1 (formerly subtype 148);PLC-148;PLC-gamma-1;PLC-II;PLC1;PLC148;PLCgamma1;triphosphoinositide phosphodiesterase
Extra Details:: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Shipping Conditions:: Blue Ice