AN301377L
Recombinant Caspase-3 Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN301377L
- Additional Names:
- SCA,CPP,Caspase-3 p,SREBP cleavage activity,Caspase,Caspase-,CPP32,CPP32B,SCA-1,Active Caspase 3,CASP3,active Caspase-3,Caspase 3,Caspase-3 p12,caspase-3,Apoptain,Yama,CASP-3,Apopain,Protein Yama,SREBP cleavage activity 1,Caspase-3 subunit p17,Caspase-3 subunit p12,caspase-3,CPP32,CPP32B,SCA-1,A830040C14Rik,apoptosis-related cysteine peptidase,apoptosis-related cysteine protease,apoptosis-related cysteine protease a,Casp3a,CC3,CPP-32,Cysteine protease CPP32,EC
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Caspase-3 protein
- Clone:
- B1144
- Uniprot:
- P42574
- Synonyms:
- apopain;CASP-3;caspase 3, apoptosis-related cysteine peptidase;caspase 3, apoptosis-related cysteine protease;caspase-3;CPP-32;CPP32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1
- Extra Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer&apos,s disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
- Shipping Conditions:
- Blue Ice