AN301373L
Recombinant TGF B Beta Receptor II Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN301373L
- Additional Names:
- MFS,LDS,FAA,AAT,TAAD,TGFR,TGF-beta receptor type,TGFBR,AAT3,FAA3,LDS1B,LDS2,LDS2B,MFS2,RIIC,TAAD2,TGFR-2,TGFbeta-RII,TGF beta Receptor II,TGFBR2,TGF-beta receptor type-2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II,FAA3,LDS1B,LDS2,LDS2B,MFS2,RIIC,TAAD2,Tgfbr2,beta receptor II (70/80kDa),beta receptor II alpha,beta receptor II beta,beta receptor II delta,beta receptor II epsilon,beta receptor II gamma,TbetaR II,TbetaR-II,TBRII,TBR-ii,TGF beta receptor type 2,TGF
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human TGF B Beta Receptor II protein
- Clone:
- B1140
- Uniprot:
- P37173
- Synonyms:
- AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;tbetaR-II;TBR-ii;TBRII;TGF-beta receptor type IIB;TGF-beta receptor type-2;TGF-beta type II receptor;TGFbeta-RII;TGFR-2;transforming growth factor beta receptor II;transforming growth factor beta receptor type IIC;Transforming growth factor-beta receptor type II;transforming growth factor, beta receptor II (70/80kDa);transforming growth factor, beta receptor II alpha;transforming growth factor, beta receptor II beta;transforming growth factor, beta receptor II delta;transforming growth factor, beta receptor II epsilon;transforming growth factor, beta receptor II gamma
- Extra Details:
- This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
- Shipping Conditions:
- Blue Ice