AN301365L
Recombinant SDHB Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN301365L
- Additional Names:
- PGL,CWS,SDHB,CWS2,IP,PGL4,SDH,SDH1,SDH2,SDHIP,PGL4,SDH,SDH1,SDH2,SdhB,SDHIP,DHSB,FLJ92337,homolog of,iron sulfur (Ip),Iron sulfur subunit,Iron sulfur subunit of complex II,Iron-sulfur subunit of complex II,mitochondrial,PGL 4,S. cerevisiae,SDH 1,subunit B,Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial,Succinate dehydrogenase [ubiquinone] iron sulfur subunit,Succinate dehydrogenase [ubiquinone] iron-sulfur subunit,Succinate Dehydrogenase 1 Iron Sulfur Subunit,Succinate
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human SDHB protein
- Clone:
- B1132
- Uniprot:
- P21912
- Synonyms:
- CWS2;IP;iron-sulfur subunit of complex II;MC2DN4;PGL4;SDH;SDH1;SDH2;SDHIP;succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Extra Details:
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
- Shipping Conditions:
- Blue Ice