AN301342L
Recombinant ASC Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN301342L
- Additional Names:
- TNS,TMS,CARD,A,Asc,TMS-,TNS1,masc,CARD5,TMS-1,9130417A21Rik,Pycard,9130417A21Rik,Asc,CARD5,masc,TMS-,TMS-1,TNS1
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Mouse ASC protein
- Clone:
- B1109
- Uniprot:
- Q9EPB4
- Synonyms:
- 9130417A21Rik;A;apoptosis-associated speck-like protein containing a CARD;Asc;CARD5;masc;PYD and CARD domain-containing protein;TMS-;TMS-1;TNS1
- Extra Details:
- This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice