AN301299L
Recombinant Phospho-IGF1R (Tyr1135/1136)/Phospho-Insulin Receptor B Beta (Tyr1150/1151) Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN301299L
- Additional Names:
- HHF,CD220,HHF5,INSR,IR,Insulin R,INSR,IR,Insulin Receptor,IGF IR,Insulin Receptor B Beta
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- A synthetic peptide corresponding to residues around (Tyr1135/1136)/(Tyr1150/1151) of Human Phospho-IGF1R/Phospho-Insulin Receptor B Beta
- Clone:
- B1062
- Uniprot:
- P06213, P08069
- Synonyms:
- CD220;CD221;HHF5;IGF-I receptor;IGFIR;IGFR;insulin receptor;insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IR;JTK13;soluble IGF1R variant 1;soluble IGF1R variant 2
- Extra Details:
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice