AN301292L
Recombinant Actinin-A Alpha1 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301292L
- Additional Names:
- ACTN,Non-muscle alpha-actinin,BDPLT,ACTN1,BDPLT15,Alpha-actinin cytoskeletal isoform,F-actin cross-linking protein,Non-muscle alpha-actinin-1,actinin,actinin 1 smooth muscle,Actinin alpha 1,ACTN 1,alpha 1,Alpha Actinin 1,Alpha actinin cytoskeletal isoform,Alpha-actinin-1,F actin cross linking protein,FLJ40884,FLJ54432,Non muscle alpha actinin 1,Actinin-A Alpha1
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Actinin-A Alpha1 protein
- Clone:
- B1055
- Uniprot:
- P12814
- Synonyms:
- actinin 1 smooth muscle;Alpha-actinin cytoskeletal isoform;alpha-actinin-1;BDPLT15;epididymis secretory sperm binding protein;F-actin cross-linking protein;non-muscle alpha-actinin-1
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice