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AN301287L

Recombinant Trk A Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:
AN301287L
Additional Names:
NTRK,NTRK1,MTC,TRK,TRK1,TRKA,Trk-A,p140-TrkA,gp140trk,High affinity nerve growth factor receptor,High affinity nerve growth factor receptor precursor,Neurotrophic tyrosine kinase receptor type 1,Oncogene TRK,p140 TrkA,p14-TrkA,Slow nerve growth,Trk A,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk A
Application:
IHC
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human Trk A protein
Clone:
B1050
Uniprot:
P04629
Synonyms:
gp140trk;high affinity nerve growth factor receptor;MTC;Neurotrophic tyrosine kinase receptor type 1;neurotrophic tyrosine kinase, receptor, type 1;Oncogene TRK;p140-TrkA;TRK;Trk-A;TRK1;TRK1-transforming tyrosine kinase protein;TRKA;tropomyosin-related kinase A;Tyrosine kinase receptor;tyrosine kinase receptor A
Extra Details:
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Shipping Conditions:
Blue Ice