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AN301282L

Recombinant BMP-4 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:
AN301282L
Additional Names:
OFC,DVR,MGC,ZGC,Bone morphogenetic protein,zbmp,MCOPS,BMP,BMP4,BMP2B,BMP2B1,MCOPS6,OFC11,ZYME,BMP 2B,BMP 4,BMP-2B,BMP-4,Bone morphogenetic protein 2B,Bone morphogenetic protein 4,MGC100779,zbmp-4,zgc:100779,DVR4,BMP-4
Application:
IHC
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human BMP-4 protein
Clone:
B1045
Uniprot:
P12644
Synonyms:
BMP2B;BMP2B1;bone morphogenetic protein 2B;bone morphogenetic protein 4;MCOPS6;OFC11;ZYME
Extra Details:
Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932], also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies.,Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair.,online information:Bone morphogenetic protein 4 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer, disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.,tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
Shipping Conditions:
Blue Ice