AN301279L
Recombinant GluR-2 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301279L
- Additional Names:
- GRIA,GLUR,GluA,HBGR,GluR-K,GRIA2,GLUR2,GLURB,GluA2,GluR-K2,HBGR2,AMPA 2,AMPA selective glutamate receptor 2,AMPA2,AMPA-selective glutamate receptor 2,GLUR 2,GLUR B,GluR K2,GluR-2,GluR-B,Glutamate receptor 2,Glutamate receptor ionotropic,Glutamate receptor ionotropic AMPA 2,GluR-2
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human GluR-2 protein
- Clone:
- B1042
- Uniprot:
- P42262
- Synonyms:
- AMPA-selective glutamate receptor 2;GluA2;gluR-2;gluR-B;GluR-K2;GLUR2;GLURB;glutamate receptor 2;Glutamate receptor ionotropic, AMPA 2;glutamate receptor, ionotropic, AMPA 2;HBGR2;NEDLIB
- Extra Details:
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->,CGG, Q->,R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology.
- Shipping Conditions:
- Blue Ice