AN301268L
Recombinant MRE11 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301268L
- Additional Names:
- MRE,HNGS,MRE11,ATLD,HNGS1,MRE11A,MRE11B,AT like disease,Ataxia telangiectasia disorder like,DNA recombination and repair protein,Double strand break repair protein MRE11A,Double-strand break repair protein MRE11A,endo/exonuclease Mre11,meiotic recombination (S. cerevisiae) 11 homolog A,Meiotic recombination 11 homolog 1,Meiotic recombination 11 homolog A,meiotic recombination 11 homolog A (S. cerevisiae),MmMRE11A,Mre 11,MRE 11a,MRE 11b,MRE11 homolog 1,MRE11 homolog A,MRE11 homolog double
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human MRE11 protein
- Clone:
- B1031
- Uniprot:
- P49959
- Synonyms:
- AT-like disease;ATLD;DNA recombination and repair protein;double-strand break repair protein MRE11;double-strand break repair protein MRE11A;endo/exonuclease Mre11;HNGS1;meiotic recombination 11 homolog 1;meiotic recombination 11 homolog A;MRE11 double strand break repair nuclease A;MRE11 homolog 1;MRE11 homolog A, double strand break repair nuclease;MRE11 homolog, double strand break repair nuclease A;MRE11 meiotic recombination 11 homolog A;MRE11 meiotic recombination 11-like protein A;MRE11A;MRE11B
- Extra Details:
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3&apos, to 5&apos, exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3&apos, to 5&apos, exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice