AN301257L
Recombinant Raf-B Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301257L
- Additional Names:
- RAFB,BRAF,B-RAF1,B-raf,BRAF1,NS7,RAFB1,serine/threonine-protein kinase B-raf,B-raf,BRAF1,B-RAF1,NS7,RAFB1,serine/threonine-protein kinase B-raf,94 kDa B raf protein,B raf 1,B Raf proto oncogene,B Raf proto oncogene serine threonine protein kinase,B RAF1,BRAF 1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),cRmil,FLJ95109,MGC126806,MGC138284,Murine sarcoma viral (v-raf) oncogene homolog B1,Murine sarcoma viral v raf oncogene homolog B1,Oncogen BRAF,oncogene BRAF1,p94,proto-oncogene
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Raf-B protein
- Clone:
- B1020
- Uniprot:
- P15056
- Synonyms:
- 94 kDa B-raf protein;B-raf;B-Raf proto-oncogene serine/threonine-protein kinase (p94);B-Raf serine/threonine-protein;B-RAF1;BRAF1;murine sarcoma viral (v-raf) oncogene homolog B1;NS7;p94;proto-oncogene B-Raf;RAFB1;serine/threonine-protein kinase B-raf;v-raf murine sarcoma viral oncogene homolog B;v-raf murine sarcoma viral oncogene homolog B1
- Extra Details:
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
- Shipping Conditions:
- Blue Ice