AN301249L
Recombinant Shh Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301249L
- Additional Names:
- HLP,HPE,MCOPCB,HHG1,HHG-1,HLP3,HPE3,MCOPCB5,SMMCI,Sonic hedgehog,Sonic Hedgehog Protein,TPT,TPTPS,SHH,HHG 1,HLP 3,Holoprosencephaly 3,HPE 3,SMMC I,Sonic Hedgehog (Drosophila) homolog,Sonic hedgehog homolog,sonic hedgehog homolog (Drosophila),Sonic hedgehog protein C-product,Shh
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Shh protein
- Clone:
- B1012
- Uniprot:
- Q15465
- Synonyms:
- HHG-1;HHG1;HLP3;HPE3;MCOPCB5;shh unprocessed N-terminal signaling and C-terminal autoprocessing domains;ShhNC;SMMCI;sonic hedgehog homolog;sonic hedgehog protein;TPT;TPTPS
- Extra Details:
- This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo.
- Shipping Conditions:
- Blue Ice