AN301238L
Recombinant Nogo B receptor Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301238L
- Additional Names:
- NUS,C6orf,C6orf68,NGBR,NUS1
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Nogo B receptor protein
- Clone:
- B1001
- Uniprot:
- Q96E22
- Synonyms:
- C6orf68;CDG1AA;cis-prenyltransferase subunit NgBR;dehydrodolichyl diphosphate syntase complex subunit NUS1;dehydrodolichyl diphosphate synthase complex subunit NUS1;di-trans,poly-cis-decaprenylcistransferase;MGC:7199;MRD55;NgBR;Nogo-B receptor;nuclear undecaprenyl pyrophosphate synthase 1 homolog;TANGO14;transport and golgi organization 14 homolog
- Extra Details:
- This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X.
- Shipping Conditions:
- Blue Ice