AN301231L
Recombinant TMEM43 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301231L
- Additional Names:
- UNQ,PRO,TMEM,ARVC,ARVD,EDMD,TMEM43,ARVC5,ARVD5,EDMD7,LUMA,UNQ2564,PRO6244
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human TMEM43 protein
- Clone:
- B990
- Uniprot:
- Q9BTV4
- Synonyms:
- ARVC5;ARVD5;EDMD7;LUMA;Protein LUMA;transmembrane protein 43
- Extra Details:
- This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
- Shipping Conditions:
- Blue Ice