AN301172L
Recombinant TRAF2 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301172L
- Additional Names:
- MGC,TRAF,TNF receptor-associated factor,MGC:45012,TRAP,TRAP3,TRAF2,TNF receptor-associated factor 2,MGC:45012,TNF receptor-associated factor 2,TRAP,TRAP3,TRAF2
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human TRAF2 protein
- Clone:
- B931
- Uniprot:
- Q12933
- Synonyms:
- E3 ubiquitin-protein ligase TRAF2;MGC:45012;RING-type E3 ubiquitin transferase TRAF2;RNF117;TNF receptor-associated factor 2;TRAP;TRAP3;tumor necrosis factor type 2 receptor associated protein 3;Tumor necrosis factor type 2 receptor-associated protein 3
- Extra Details:
- TNF receptor associated factor 2(TRAF2) Homo sapiens The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation.
- Shipping Conditions:
- Blue Ice