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AN301159L

Recombinant NF2 Monoclonal Antibody

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£221.40

Was £246.00

SKU:
AN301159L
Additional Names:
Neurofibromin,Neurofibromatosis type,NF2,ACN,BANF,SCH,merlin,Bilateral acoustic neuroma,CAN,MERL_HUMAN,Moesin ezrin radixin like protein,Moesin ezrin radizin like,Moesin-ezrin-radixin-like,Neurofibromatosis 2,Neurofibromatosis type 2,Neurofibromatosis2,NF 2,Schwannomerlin,Schwannomin,Neurofibromin 2,neurofibromin 2 (merlin),NF2
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human NF2 protein
Clone:
B918
Uniprot:
P35240
Synonyms:
ACN;BANF;bilateral acoustic neurofibromatosis;merlin;merlin-1;moesin-ezrin-radixin like;moesin-ezrin-radixin-like protein;moesin-ezrin-radizin-like protein;neurofibromin 2 (bilateral acoustic neuroma);Neurofibromin-2;SCH;schwannomerlin;schwannomin
Extra Details:
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development, in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
Shipping Conditions:
Blue Ice