Recombinant BIRC2 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:: AN301153L
Additional Names:: RNF,API,cIAP,BIRC,c-IAP,API1,HIAP2,Hiap-2,MIHB,RNF48,c-IAP1,cIAP1,BIRC2,BIRC2
Application:: IHC, WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human BIRC2 protein
Clone:: B912
Uniprot:: Q13490
Synonyms:: API1;apoptosis inhibitor 1;baculoviral IAP repeat-containing protein 2;c-IAP1;cellular inhibitor of apoptosis 1;cIAP1;Hiap-2;HIAP2;IAP homolog B;IAP-2;inhibitor of apoptosis protein 2;MIHB;NFR2-TRAF signalling complex protein;RING finger protein 48;RING-type E3 ubiquitin transferase BIRC2;RNF48;TNFR2-TRAF-signaling complex protein 2
Extra Details:: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.