Recombinant Phospho-p53 (Ser46) Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:: AN301140L
Additional Names:: BCC,LFS,TRP,BMFS,Antigen NY-CO,Tumor protein,Phosphoprotein p,Tumor suppressor p,Mutant tumor protein,Cellular tumor antigen p,Transformation related protein,BCC7,LFS1,P53,TRP53,TP53,BMFS5,Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,Mutant tumor protein 53,p53 tumor suppressor,Phosphoprotein p53,Transformation related protein 53,Tumor protein 53,Tumor protein p53,Tumor suppressor p53,BCC7,LFS1,P53,TRP53,tumor protein p53,Antigen NY-CO-13,BCC7,Cellular tumor antigen
Application:: IHC, WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: A synthetic peptide corresponding to residues around (Ser46) of Human Phospho-p53
Clone:: B895
Uniprot:: P04637
Synonyms:: antigen NY-CO-13;BCC7;BMFS5;cellular tumor antigen p53;LFS1;mutant tumor protein 53;P53;p53 tumor suppressor;phosphoprotein p53;transformation-related protein 53;TRP53;tumor protein 53;Tumor suppressor p53;tumor supressor p53
Extra Details:: TP53(tumor protein p53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

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