Recombinant GAD-65/67 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:: AN301129L
Additional Names:: GAD,GAD2,GAD65,65 kDa glutamic acid decarboxylase,DCE 2,DCE2,GAD 2,GAD 65,GAD-2,GAD-65,Glutamate decarboxylase 2,Glutamate decarboxylase 2 (pancreas),Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa),Glutamate Decarboxylase 65,Glutamate decarboxylase 65 kDa isoform,Glutamic Acid Decarboxylase 2,Glutamic Acid Decarboxylase 65,MGC161605,MGC161607,GAD-65/67
Application:: IHC, WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human GAD-65/67 protein
Clone:: B884
Uniprot:: Q05329, Q99259
Synonyms:: 65 kDa glutamic acid decarboxylase;67 kDa glutamic acid decarboxylase;CPSQ1;DEE89;GAD;GAD-65;GAD-67;GAD65;glutamate decarboxylase 1;glutamate decarboxylase 1 (brain, 67kDa);glutamate decarboxylase 2;glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa);Glutamate decarboxylase 65 kDa isoform;Glutamate decarboxylase 67 kDa isoform;Glutamate decarboxylase-2 (pancreas);SCP
Extra Details:: GAD1(glutamate decarboxylase 1) Homo sapiens This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

Shipping Conditions:: Blue Ice