AN301086L
Recombinant RIP Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301086L
- Additional Names:
- RIPK,RIP,RIP-1,RIP1,RIPK1,Cell death protein RIP,FLJ39204,OTTHUMP00000039163,Receptor (TNFRSF) interacting serine threonine kinase 1,Receptor interacting protein,receptor interacting protein 1,Receptor interacting protein kinase 1,Receptor interacting serine threonine protein kinase 1,Receptor TNFRSF interacting serine threonine kinase 1,Receptor-interacting protein 1,Receptor-interacting serine/threonine-protein kinase 1,Rinp,RIP 1,RIPK 1,Serine threonine protein kinase
- Application:
- IHC, WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human RIP protein
- Clone:
- B841
- Uniprot:
- Q13546
- Synonyms:
- AIEFL;cell death protein RIP;IMD57;receptor (TNFRSF)-interacting serine-threonine kinase 1;receptor-interacting protein 1;receptor-interacting protein kinase 1;receptor-interacting serine/threonine-protein kinase 1;RIP;RIP-1;RIP1;serine/threonine-protein kinase RIP
- Extra Details:
- ATP + a protein = ADP + a phosphoprotein.,Promotes apoptosis and activation of NF-kappa-B. Required for TNFRSF1A mediated activation of NF-kappa-B.,PTM:Autophosphorylated on serine and threonine residues.,PTM:Proteolytically cleaved by caspase-8 during TNF-induced apoptosis. Cleavage abolishes NF-kappa-B activation and enhances pro-apototic signaling through the TRADD-FADD interaction.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 death domain.,similarity:Contains 1 protein kinase domain.,subunit:Binds to the death domain of TNFRSF6 and TRADD. Is recruited by TRADD to TNFRSF1A in a TNF-dependent process. Binds RIPK3, UBCE7IP1 isoform 3 (ZIN), EGFR, IKBKG, TRAF1, TRAF2 and TRAF3. Interacts with BNLF1. Interacts with SQSTM1 upon TNF-alpha stimulation. May interacts with MAVS/IPS1.
- Shipping Conditions:
- Blue Ice