AN301071L
Recombinant Fibrillarin Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301071L
- Additional Names:
- FIB,FIB1,FLRN,FBL,fibrillarin,Nop1,RNU3IP1,FBL
- Application:
- IHC, WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Fibrillarin protein
- Clone:
- B826
- Uniprot:
- P22087
- Synonyms:
- 34 kDa nucleolar scleroderma antigen;34-kD nucleolar scleroderma antigen;FIB;FLRN;histone-glutamine methyltransferase;Nop1;RNA, U3 small nucleolar interacting protein 1;RNU3IP1;rRNA 2'-O-methyltransferase fibrillarin;U6 snRNA 2'-O-methyltransferase fibrillarin
- Extra Details:
- This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
- Shipping Conditions:
- Blue Ice