AN301056L
Recombinant c-Myc Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN301056L
- Additional Names:
- bHLHe,MYC BHLHE,MRTL,MYCC,bHLHe39,c-Myc,MYC,MYC BHLHE39,AU016757,Avian myelocytomatosis viral oncogene homolog,c Myc,Class E basic helix-loop-helix protein 39,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,Myc2,myc-related translation/localization regulatory factor,Myelocytomatosis oncogene,Niard,Nird,Oncogene Myc,OTTHUMP00000158589,Proto-oncogene c-Myc,Protooncogene homologous to myelocytomatosis virus,RNCMYC,Transcription factor p64,Transcriptional regulator Myc-A,V-Myc
- Application:
- IHC, WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human c-Myc protein
- Clone:
- B811
- Uniprot:
- P01106
- Synonyms:
- avian myelocytomatosis viral oncogene homolog;bHLHe39;c-Myc;class E basic helix-loop-helix protein 39;MRTL;myc proto-oncogene protein;myc-related translation/localization regulatory factor;MYCC;proto-oncogene c-Myc;transcription factor p64;v-myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog
- Extra Details:
- MYC(v-myc avian myelocytomatosis viral oncogene homolog) Homo sapiens The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt&apos,s lymphomas, suggesting its importance in the normal function of this gene.
- Shipping Conditions:
- Blue Ice