AN300969L
Recombinant NRAS Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300969L
- Additional Names:
- ALPS,HRAS,NRAS,ALPS4,CMNS,N-ras,NCMS,NRAS1,NS6,GTPase NRas,GTPase,HRAS1,RASN,Transforming protein N-Ras,AV095280,N ras,N ras protein part 4,Neuroblastoma RAS viral (v ras) oncogene homolog,OTTHUMP00000013879,OTTMUSP00000023521,Transforming protein N Ras,v ras neuroblastoma RAS viral oncogene homolog,N-RAS
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human NRAS protein
- Clone:
- B720
- Uniprot:
- P01111
- Synonyms:
- ALPS4;CMNS;GTPase NRas;N-ras;N-ras protein part 4;NCMS;neuroblastoma RAS viral (v-ras) oncogene homolog;neuroblastoma RAS viral oncogene homolog;NRAS1;NS6;transforming protein N-Ras;v-ras neuroblastoma RAS viral oncogene homolog
- Extra Details:
- This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
- Shipping Conditions:
- Blue Ice