AN300945L
Recombinant CD38 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300945L
- Additional Names:
- cADPr hydrolase,ADP-ribosyl cyclase,cyclic ADP-ribose hydrolase,Acute lymphoblastic leukemia cells antigen CD,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase,CD38,ADPRC 1,ADPRC1,Acute lymphoblastic leukemia cells antigen CD38,ADP ribosyl cyclase,ADP-ribosyl cyclase 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,cADPr hydrolase 1,CD38 antigen,CD38 molecule,CD38H,Cyclic ADP ribose hydrolase,EC 3.2.2.5,I-19,NIMR5 antigen,p45,ADP-ribosyl,T10,cyclase,2'-phospho-ADP-ribosyl
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human CD38 protein
- Clone:
- B892
- Uniprot:
- P28907
- Synonyms:
- 2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADPRC 1;ADPRC1;CD38 antigen (p45);cluster of differentiation 38;cyclic ADP-ribose hydrolase 1;ecto-nicotinamide adenine dinucleotide glycohydrolase;NAD(+) nucleosidase;T10
- Extra Details:
- The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5&apos,-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice