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AN300944L

Recombinant Ubiquitin K48 Monoclonal Antibody

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£221.40

Was £246.00

SKU:
AN300944L
Additional Names:
HEL-S,UBB,HEL-S-50,ubiquitin B,Polyubiquitin-B,Ubiquitin,HEL-S-50,ubiquitin B
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human Ubiquitin K48 protein
Clone:
B891
Uniprot:
P0CG47, P0CG48, P62979, P62987
Synonyms:
40S ribosomal protein S27a;CEP52;CEP80;epididymis luminal protein 112;epididymis secretory protein Li 50;HEL-S-50;HEL112;HMG20;HUBCEP52;L40;polyubiquitin B;polyubiquitin-B;polyubiquitin-C;RPL40;S27A;UBA80;UBC;UBCEP1;UBCEP80;Ubiquitin A-52 residue ribosomal protein fusion product 1;ubiquitin and ribosomal protein S27a;ubiquitin C;ubiquitin carboxyl extension protein 52;ubiquitin carboxyl extension protein 80;ubiquitin-40S ribosomal protein S27a;ubiquitin-52 amino acid fusion protein;ubiquitin-60S ribosomal protein L40;ubiquitin-CEP52;ubiquitin-CEP80
Extra Details:
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer&apos,s disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice