AN300936L
Recombinant CDK4 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300936L
- Additional Names:
- Crk,MGC,Cell division kinase,cyclin-dependent kinase,Cyclin dependent kinase,Cell division protein kinase,Melanoma cutaneous malignant,PSK-J,PSK J,p34 cdk,CMM,CDK,CDK4,CMM3,PSK-J3,cyclin-dependent kinase 4,Cdk 4,CDK4 protein,Cell division kinase 4,Cell division protein kinase 4,CMM 3,Crk3,Cyclin dependent kinase 4,Melanoma cutaneous malignant 3,MGC14458,p34 cdk4,PSK J3,CMM3,cyclin-dependent kinase 4,PSK-J3
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human CDK4 protein
- Clone:
- B883
- Uniprot:
- P11802
- Synonyms:
- cell division protein kinase 4;CMM3;cyclin-dependent kinase 4;PSK-J3
- Extra Details:
- CDK4(cyclin dependent kinase 4) Homo sapiens The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
- Shipping Conditions:
- Blue Ice