Recombinant CHOP Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:: AN300931L
Additional Names:: DDIT,GADD,DNA damage inducible transcript,DDIT3,CEBPZ,CHOP,CHOP-10,CHOP10,GADD153,C/EBPzeta,DDIT3 / CHOP,DNA damage inducible transcript 3,CEBPZ,CHOP,CHOP10,CHOP-10,DNA damage inducible transcript 3,GADD153,C/EBP homologous protein,C/EBP Homology Protein,C/EBP zeta,C/EBP-homologous protein,C/EBP-homologous protein 10,CCAAT/enhancer binding protein homologous protein,CHOP 10,DDIT 3,DDIT-3,DNA damage-inducible transcript 3 protein,GADD 153,Growth Arrest and DNA Damage Inducible Protein
Application:: IHC, WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human CHOP protein
Clone:: B878
Uniprot:: P35638
Synonyms:: AltDDIT3;alternative DDIT3 protein;C/EBP zeta;C/EBP-homologous protein;c/EBP-homologous protein 10;C/EBPzeta;CCAAT/enhancer-binding protein homologous protein;CEBPZ;CHOP;CHOP-10;CHOP10;DNA damage-inducible transcript 3 protein;GADD153;growth arrest and DNA damage-inducible protein GADD153
Extra Details:: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

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