AN300927L
Recombinant PRKACA Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300927L
- Additional Names:
- PPNAD,PRKACA,PKACA,PPNAD4,cAMP dependent protein kinase alpha catalytic subunit,cAMP dependent protein kinase beta catalytic subunit,cAMP dependent protein kinase catalytic beta subunit isoform 4ab,cAMP dependent protein kinase catalytic subunit alpha,cAMP dependent protein kinase catalytic subunit beta,cAMP-dependent protein kinase catalytic subunit alpha,isoform 1,KAPCA,PKA C alpha,PKA C beta,PKA C-alpha,PKACB,PRKACAA,PRKACB,Protein kinase A catalytic subunit,Protein kinase A catalytic
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human PRKACA protein
- Clone:
- B874
- Uniprot:
- P17612
- Synonyms:
- CAFD1;cAMP-dependent protein kinase catalytic subunit alpha;PKA C-alpha;PKACA;PPNAD4;protein kinase A catalytic subunit;protein kinase, cAMP-dependent, alpha catalytic subunit;protein kinase, cAMP-dependent, catalytic, alpha
- Extra Details:
- This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing&apos,s syndrome.
- Shipping Conditions:
- Blue Ice