Recombinant CD45 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:: AN300907L
Additional Names:: B220,CD45,CD45R,GP180,L-CA,LCA,LY5,T200,PTPRC,CD45 antigen,CD45R0,Ly-5,protein tyrosine phosphatase,receptor type,Receptor-type tyrosine-protein phosphatase C,CD45RO,Receptor-type tyrosine-protein phosphatase CLeukocyte common antigen (L-CA),T200,c polypeptide,CD 45,homolog of,Leukocyte common antigen,loc,Lyt-4,OTTHUMP00000033813,OTTHUMP00000033816,OTTHUMP00000033817,OTTHUMP00000038574,Protein tyrosine phosphatase receptor type c polypeptide,protein tyrosine phosphatase,receptor
Application:: IHC, WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human CD45 protein
Clone:: B854
Uniprot:: P08575
Synonyms:: B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;LY5;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
Extra Details:: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling.

Shipping Conditions:: Blue Ice