Recombinant Oct-4 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:: AN300895L
Additional Names:: POU5F,OTF,POU5F1,OTF-3,OTF3,OTF4,Oct-3,Oct-4,OCT-3/4,Octamer-4,POU Class 5 Homoeobox 1,POU Domain Class 5 Transcription Factor 1,POU5F1/OCT4
Application:: WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human Oct-4 protein
Clone:: B842
Uniprot:: Q01860
Synonyms:: Oct-3;Oct-4;OCT3;OCT4;octamer-binding protein 3;octamer-binding protein 4;octamer-binding transcription factor 3;OTF-3;OTF3;OTF4;POU domain transcription factor OCT4;POU domain, class 5, transcription factor 1;POU-type homeodomain-containing DNA-binding protein
Extra Details:: This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation withThe Ewing&apos,s sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One ofThe AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.