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AN300845L

Recombinant CD10 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:
AN300845L
Additional Names:
SCA,Neutral endopeptidase 24.,CALLA,CD10,CMT2T,NEP,SCA43,SFE,MME,Atriopeptidase,Common acute lymphocytic leukemia antigen,Enkephalinase,Neprilysin,Neutral endopeptidase,Neutral endopeptidase 24.11,Skin fibroblast elastase,EPN,NEP,gp100,CD10 antigen,CD10),DKFZp686O16152,EC 3.4.24.11,enkephalinase),Membrane metallo endopeptidase,Membrane metallo endopeptidase (neutral endopeptidase,Membrane metallo endopeptidase variant 1,Membrane metallo endopeptidase variant 2,Membrane
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human CD10 protein
Clone:
B788
Uniprot:
P08473
Synonyms:
atriopeptidase;CALLA;CD10;CMT2T;common acute lymphocytic leukemia antigen;Enkephalinase;membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10);membrane metallo-endopeptidase variant 1;membrane metallo-endopeptidase variant 2;NEP;neprilysin;neprilysin-390;neprilysin-411;neutral endopeptidase 24.11;SCA43;SFE;skin fibroblast elastase
Extra Details:
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb.
Shipping Conditions:
Blue Ice