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AN300838L

Recombinant Dnmt1 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:
AN300838L
Additional Names:
MGC,CXXC,DNA methyltransferase,CXXC finger protein 9|DNA methyltransferase,ADCADN,AIM,CXXC9,DNMT,HSN1E,MCMT,m.HsaI,DNMT1,CXXC finger protein 9|DNA methyltransferase 1,DNA methyltransferase 1,FLJ16293,MGC104992,ADCADN,AIM,CXXC9,DNA methyltransferase 1,DNMT,HSN1E,m.HsaI,MCMT,CXXC finger protein 9,CXXC-type zinc finger protein 9,DNA (cytosine 5 ) methyltransferase 1,DNA (cytosine-5)-methyltransferase 1,DNA methyltransferase HsaI,DNA methyltransferase M.HsaI.,DNA MTase,DNA MTase HsaI,DNMT
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human Dnmt1 protein
Clone:
B781
Uniprot:
P26358
Synonyms:
ADCADN;AIM;CXXC-type zinc finger protein 9;CXXC9;DNA (cytosine-5-)-methyltransferase 1;DNA (cytosine-5)-methyltransferase 1;DNA methyltransferase HsaI;DNA MTase HsaI;DNMT;HSN1E;m.HsaI;MCMT
Extra Details:
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice