Recombinant Lamin A/C Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:: AN300833L
Additional Names:: EMD,LDP,LMN,PRO,CDCD,LMNL,CMT2B,LMNA,CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,FPLD2,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNC,LMNL1,MADA,PRO1,lamin,Lamin A/C,70 kDa lamin,Cardiomyopathy dilated 1A (autosomal dominant),Lamin A,Lamin A/C like 1,Lamin C,Lamin-A/C,Limb girdle muscular dystrophy 1B (autosomal dominant),LMN 1,LMN A,LMN C,Prelamin A/C,Renal carcinoma antigen NY REN 32,Renal carcinoma antigen NYREN32,Renal carcinoma antigen NY-REN-32,Lamin A/C (phospho Ser392)
Application:: WB
Concentration:: 0.2 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human Lamin A/C protein
Clone:: B776
Uniprot:: P02545
Synonyms:: 70 kDa lamin;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;epididymis secretory sperm binding protein;FPL;FPLD;FPLD2;HGPS;IDC;lamin;lamin A/C-like 1;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;mandibuloacral dysplasia type A;prelamin-A/C;PRO1;renal carcinoma antigen NY-REN-32
Extra Details:: Lamin A/C(LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Shipping Conditions:: Blue Ice