AN300819L
Recombinant MDR1 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300819L
- Additional Names:
- MDR,PGY,ABC,ABCB,P-glycoprotein,Phospholipid transporter ABCB,ATP-dependent translocase ABCB,ATP-binding cassette sub-family B member,ABC20,CD243,CLCS,GP170,MDR1,P-GP,PGY1,P Glycoprotein,ABCB1,ATP-binding cassette sub-family B member 1,ATP-dependent translocase ABCB1,P-glycoprotein 1,Phospholipid transporter ABCB1,MDR-1,P-gp,gp170,ABC-B1,ATP binding cassette,Colchicin sensitivity,Doxorubicin resistance,member 1,Multidrug resistance 1,Multidrug resistance protein 1,P glycoprotein 1,P gp,sub
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human MDR1 protein
- Clone:
- B762
- Uniprot:
- P08183
- Synonyms:
- ABC20;ATP-binding cassette sub-family B member 1;ATP-binding cassette, sub-family B (MDR/TAP), member 1;ATP-dependent translocase ABCB1;CD243;CLCS;colchicin sensitivity;doxorubicin resistance;GP170;MDR1;multidrug resistance protein 1;p-170;P-glycoprotein 1;P-GP;PGY1;phospholipid transporter ABCB1
- Extra Details:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
- Shipping Conditions:
- Blue Ice