AN300817L
Recombinant 4E-BP1 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300817L
- Additional Names:
- 4EBP,eIF4E binding protein,eukaryotic translation initiation factor 4E-binding protein,4E-BP,EIF4EBP,EIF4EBP1,4E-BP1,4EBP1,BP-1,PHAS-I,eukaryotic translation initiation factor 4E-binding protein 1,BP 1,eIF4E binding protein 1,eIF4E-binding protein 1,PHASI,Phosphorylated heat- and acid-stable protein regulated by insulin 1,4EBP1,4E-BP1,BP-1,eukaryotic translation initiation factor 4E-binding protein 1,PHAS-I
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human 4E-BP1 protein
- Clone:
- B760
- Uniprot:
- Q13541
- Synonyms:
- 4E-BP1;4EBP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1
- Extra Details:
- This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5&apos, end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
- Shipping Conditions:
- Blue Ice