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AN300793L

Recombinant GCLC Monoclonal Antibody

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£221.40

Was £246.00

SKU:
AN300793L
Additional Names:
GSH,Glutamate cysteine ligase catalytic subunit,GCLC,GCL,GCS,GLCL,GLCLC,EC 6.3.2.2,Gamma ECS,Gamma glutamylcysteine synthetase,Gamma-ECS,Gamma-glutamylcysteine synthetase,GCS heavy chain,Glutamate cysteine ligase catalytic subunit,Glutamate--cysteine ligase catalytic subunit,GSH1,GCSc-G Gamma
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human GCLC protein
Clone:
B736
Uniprot:
P48506
Synonyms:
gamma-ECS;gamma-glutamylcysteine synthetase;GCL;GCS;GCS heavy chain;GLCL;GLCLC;glutamate--cysteine ligase catalytic subunit
Extra Details:
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Shipping Conditions:
Blue Ice