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AN300739L

Recombinant JNK1/2/3 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:
AN300739L
Additional Names:
MAPK,PRKM,SAPK,JNK1A,JNK21B,MAPK8,JNK,JNK-46,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1,SAPK1c,AI849689,c Jun N terminal kinase 1,C-JUN kinase 1,c-Jun N-terminal kinase 1,EC 2.7.11.24,JNK 1,MAP kinase 8,MAPK 8,Mitogen activated protein kinase 8,mitogen-activated,Mitogen-activated protein kinase 8,MK08,p54 gamma,Protein kinase,Protein kinase JNK1,SAPK 1,SAPK gamma,Stress-activated protein kinase 1,Stress-activated protein kinase JNK1
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human JNK1/2/3 protein
Clone:
B678
Uniprot:
P45983, P45984, P53779
Synonyms:
c-Jun kinase 2;c-Jun N-terminal kinase 1;c-Jun N-terminal kinase 2;c-Jun N-terminal kinase 3;JNK;JNK-46;JNK-55;JNK1;JNK1A2;JNK2;JNK21B1/2;JNK2A;JNK2ALPHA;JNK2B;JNK2BETA;JNK3;JNK3 alpha protein kinase;JNK3A;Jun kinase;JUN N-terminal kinase;MAP kinase 10;MAP kinase 8;MAP kinase 9;MAP kinase p49 3F12;MAPK 9;mitogen-activated protein kinase 10;mitogen-activated protein kinase 8;mitogen-activated protein kinase 9;p493F12;p54a;p54aSAPK;p54bSAPK;PRKM10;PRKM8;PRKM9;SAPK;SAPK1;SAPK1a;SAPK1b;SAPK1c;stress activated protein kinase beta;stress-activated protein kinase 1;stress-activated protein kinase 1a;stress-activated protein kinase 1b;stress-activated protein kinase 1c;Stress-activated protein kinase JNK1;stress-activated protein kinase JNK2;stress-activated protein kinase JNK3
Extra Details:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.
Shipping Conditions:
Blue Ice