AN300719L
Recombinant LRP6 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300719L
- Additional Names:
- LRP,ADCAD,STHAG,LRP6,ADCAD2,STHAG7,C030016K15Rik,FLJ90062,FLJ90421,LDL receptor related protein 6,Low density lipoprotein receptor related protein 6,Low-density lipoprotein receptor-related protein 6,LRP-6,OTTHUMP00000238979,OTTHUMP00000238980,OTTHUMP00000238982
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human LRP6 protein
- Clone:
- B658
- Uniprot:
- O75581
- Synonyms:
- ADCAD2;low-density lipoprotein receptor-related protein 6;LRP-6;STHAG7
- Extra Details:
- This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
- Shipping Conditions:
- Blue Ice