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AN300712L

Recombinant MMP2 Monoclonal Antibody

Size

£221.40

Was £246.00

SKU:
AN300712L
Additional Names:
TBE,CLG,Matrix Metalloproteinase,MMP,CLG4,CLG4A,MMP-2,MMP-II,MONA,TBE-1,MMP2,72 kDa Gelatinase,72 kDa Type IV Collagenase,Gelatinase A,Matrix Metalloproteinase-2,72kD type IV collagenase,72kDa gelatinase,72kDa type IV collagenase),CLG 4,CLG 4A,Collagenase Type 4 alpha,Collagenase type IV A,Gelatinase alpha,Gelatinase neutrophil,Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase,Matrix Metalloproteinase 2,Matrix metalloproteinase 2 (gelatinase A,Matrix
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human MMP2 protein
Clone:
B651
Uniprot:
P08253
Synonyms:
72 kDa gelatinase;72 kDa type IV collagenase;CLG4;CLG4A;collagenase type IV-A;Gelatinase A;matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase);matrix metalloproteinase-2;matrix metalloproteinase-II;MMP-2;MMP-II;MONA;neutrophil gelatinase;TBE-1
Extra Details:
Matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis.
Shipping Conditions:
Blue Ice