AN300707L
Recombinant MDM2 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300707L
- Additional Names:
- hdm,MDM,MDM2,ACTFS,HDMX,hdm2,Double minute 2 protein,E3 ubiquitin-protein ligase Mdm2,Hdm 2,MDM 2,MDM2 oncogene E3 ubiquitin protein ligase,Mdm2 p53 E3 ubiquitin protein ligase homolog,Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa,MDM2BP,Mouse Double Minute 2,MTBP,Murine Double Minute Chromosome 2,Oncoprotein Mdm2,p53 Binding Protein Mdm2,p53-binding protein Mdm2,Ubiquitin protein ligase E3 Mdm2
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human MDM2 protein
- Clone:
- B646
- Uniprot:
- Q00987
- Synonyms:
- ACTFS;Double minute 2 protein;double minute 2, human homolog of; p53-binding protein;E3 ubiquitin-protein ligase Mdm2;hdm2;HDMX;LSKB;MDM2 oncogene, E3 ubiquitin protein ligase;MDM2 proto-oncogene, E3 ubiquitin protein ligase;Mdm2, p53 E3 ubiquitin protein ligase homolog;Mdm2, transformed 3T3 cell double minute 2, p53 binding protein;oncoprotein Mdm2;p53-binding protein Mdm2;RING-type E3 ubiquitin transferase Mdm2
- Extra Details:
- This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
- Shipping Conditions:
- Blue Ice